수의미생물학 2, 수의미생물학실습 2

• 학사: 충북대학교 약학대학 약학과

• 석사: Korea Advanced Institute of Science and Technology (KAIST), 생명과학과

• 박사: 충북대학교 대학원 약학과

• 1991-1995 Research Scientist: LG Biotech Institute at Daejeon

• 1998-1998 Research associate: Korea Research Institute of Bioscience and Biotechnology (KRIBB), Division of Oncogenic virology

• 1998-2001 Research associate: Department of Microbiology, University of Tennessee at Knoxville, Tennessee, USA

• 2002-present Professor: Lab. of Microbiology, College of Veterinary Medicine, Jeonbuk national University

• 2002-2002 Visiting Scientist: Department of Microbiology, University of Tennessee at Knoxville, Tennessee, USA

• 2016-2017 Visiting Scholar at University of California, San Diego (UCSD), La Jolla, CA92093. Study on the molecular role of macrophage in colitis and asthma

• 2013-2015 Director, Bio-Safety Research Institute, Jeonbuk National University, Republic of Korea (https://biosafety.jbnu.ac.kr)

• 2018-2020Dean, College of Veterinary Medicine, Jeonbuk National University, Republic of Korea
• 2021-presentDirector, Core Facility Center of Zoonosis Research, Jeonbuk National University, Republic of Korea (funded by National Research Foundation, Korean Government)

• 매개체 전파 바이러스 질환 (flavivirus, severe fever with thrombocytopenia syndrome virus, Chikungunya virus 등)의 분자.세포 면역학적 병리 기작

• 생식기 및 호흡기 바이러스 감염(herpes virus, influenza virus, SARS-CoV-2 등)에 의한 선천성 및 적응 면역 반응

• 기저질환의 바이러스 감염 유도 악화에 대한 분자.세포 면역학적 병리 기작

• Jin Young Choi, Hee Won Byeon, Seong Ok Park, Erdenebileg Uyangaa , Koanhoi Kim and Seong Kug Eo. Inhibition of NADPH oxidase 2 enhances resistance to viral neuroinfammation by facilitating M1-polarization of macrophages at the extraneural tissues. Journal of Neuroinflammation. 21:115 (2024)

• Younghoon Lee, Minjun Seo, Suk-hyun Yun, Minyeong Yu, Hyo Jin Kim, Hye Won Cho, Hee Won Byeon, Seong Ok Park, Erdenebileg Uyangaa, Hyunjin Jeon, Minhyeong Lee, Young Do Kwon, Seong Kug Eo. Inhibitory peptides derived from Hepatitis C virus NS5A for reducing clinical symptoms of dengue virus infection. Antiviral Research 231: 106018 (2024)

• Jeong JS, Choi JY, Kim JS, Park SO, Kim W, Yoon YG, Park HJ, Park KH, Kim DH, Kim JM, Koh GY, Seong Kug Eo, Lee YC. SARS-CoV-2 infection in severe asthma is associated with worsening of COVID-19 through respiratory NLRP3 inflammasome activation. Allergy 78:287-290 (2023)

• Patil AM, Choi JY, Park SO, Uyangaa E, Kim B, Kim K, Seong Kug Eo. Type I IFN signaling limits hemorrhage-like disease after infection with Japanese encephalitis virus through modulating a prerequisite infection of CD11b+Ly-6C+ monocytes. Journal of Neuroinflammation, 18:136 (2021)

• Choi JY, Kim JH, Hossain FMA, Uyangaa E, Park SO, Kim B, Kim K, Seong Kug Eo. Indispensable role of CX3CR1+ dendritic cells in regulation of virus-induced neuroinflammation through rapid development of antiviral immunity in peripheral lymphoid tissues. Frontiers in Immunology 10:1467 (2019)

• Kim JH, Patil AM, Choi JY, Kim SB, Uyangaa E, Hossain FM, Park SY, Lee JH, Seong KugEo. CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4+Foxp3+ T and IL-17+CD4+ Th17 cells. Journal of Neuroinflammation 13:223 (2016)

• Kim JH, Patil AM, Choi JY, Kim SB, Uyangaa E, Hossain FM, Park SY, Lee JH, Seong Kug Eo. CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4+Foxp3+TandIL-17+CD4+Th17cells. Journal of Neuroinflammation 13:223 (2016)

• Uyangaa E, Kim JH, Patil AM, Choi JY, Kim SB, Seong Kug Eo.. Distinct Upstream Role of Type I IFN Signaling in Hematopoietic Stem Cell-Derived and Epithelial Resident Cells for Concerted Recruitment of Ly-6Chi Monocytes and NK Cells via CCL2-CCL3 Cascade. PLoS Pathogens 11:e1005256 (2015)

• Kim SB, Choi JY, Kim JH, Uyangaa E, Patil AM, Park SY, Lee JH, Kim K, Han YW, Seong Kug Eo.. Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6Chimonocytedifferentiation. Journal of Neuroinflammation 12:216 (2015)

• Han YW, Choi JY, Uyangaa E, Kim SB, Kim JH, Kim BS, Kim K, Seong Kug Eo. Distinct dictation of Japanese encephalitis virus-induced neuroinflammation and lethality via triggering TLR3 and TLR4 signal pathways. PLoS Pathogens 10:e1004319 (2014).

• Aleyas AG, Han YW, Patil AM, Kim SB, Kim K, Eo SK. Impaired cross-presentation of CD8α+ CD11c+ dendritic cells by Japanese encephalitis virus in a TLR2/MyD88 signal pathway-dependent manner. Eur J Immunol. 2012 Oct;42(10):2655-66.

• Rahman MM, Uyangaa E, Han YW, Kim SB, Kim JH, Choi JY, Eo SK. Oral co-administration of live attenuated Salmonella enterica serovar Typhimurium expressing chicken interferon-α and interleukin-18 enhances the alleviation of clinical signs caused by respiratory infection with avian influenza virus H9N2. Vet Microbiol. 2012 Jun 15;157(3-4):448-55

• Aleyas AG, Han YW, George JA, Kim B, Kim K, Lee CK, Eo SK. Multifront assault on antigen presentation by Japanese encephalitis virus subverts CD8+ T cell responses. J Immunol. 2010 Aug 1;185(3):1429-41.

• Aleyas AG, George JA, Han YW, Rahman MM, Kim SJ, Han SB, Kim BS, Kim K, Eo SK. Functional modulation of dendritic cells and macrophages by Japanese encephalitis virus through MyD88 adaptor molecule-dependent and -independent pathways. J Immunol. 2009 Aug 15;183(4):2462-74.

• 면역학 (대한면역학회 감수) 도서출판 대한의학. Immunology (8th eds), Edited by David Male, Jonathan Brostoff, David Roth, Ivan Roitt (2015)

• 수의면역학 (한국수의면역학학협의회) 도서출판 한미의학. Veterinary Immunology: An Introduction (8th eds), Edited by Ian R. Tizard, published by arrangement with Elsevier Inc. (2009)